Lysosome stabilization by adjuvant arthritis serum
نویسندگان
چکیده
منابع مشابه
Long-Term Treatment by Vitamin B1 and Reduction of Serum Proinflammatory Cytokines, Hyperalgesia, and Paw Edema in Adjuvant-Induced Arthritis
Introduction: Immune system is involved in the etiology and pathophysiology of inflammation and vitamins are important sources of substances inducing nonspecific immunomodulatory effects. Given the proinflammatory role of cytokines in the inflammation and pain induction, this study aimed to assess the effects of long-term administration of vitamin B1 on the proinflammatory cytokines, edema, and...
متن کاملlong-term treatment by vitamin b1 and reduction of serum proinflammatory cytokines, hyperalgesia, and paw edema in adjuvant-induced arthritis
introduction: immune system is involved in the etiology and pathophysiology of inflammation and vitamins are important sources of substances inducing nonspecific immunomodulatory effects. given the proinflammatory role of cytokines in the inflammation and pain induction, this study aimed to assess the effects of long-term administration of vitamin b1 on the proinflammatory cytokines, edema, and...
متن کاملNeutrophils and adjuvant arthritis.
The role of neutrophils in immunologically mediated inflammatory reactions has been controversial, especially for reactions that involve a morphological predominance of lymphocytes. Another matter of controversy has been the extent to which infiltration of monocytes and lymphocytes into tissues requires a prior presence of neutrophils, as opposed to the complete independence of a mononuclear ce...
متن کاملThe Stabilization of Serum Lipid Emulsions by Serum Phospholipids
Clarity of high lipid sera is closely correlated with elevated proportions of serum phospholipids, and lipemia (milkiness) with low proportions of phospholipids. Clear high lipid sera occur uniquely in obstructive jaundice, both intra- and extrahepatic in origin. Destruction of the polar nature of serum "lecithin" by enzymatic hydrolysis, using Cl. welchii lecithinase, results in a degree of li...
متن کاملLysosome-Dependent Activation of Human Dendritic Cells by the Vaccine Adjuvant QS-21
The adjuvant properties of the saponin QS-21 have been known for decades. It is a component of the Adjuvant System AS01 that is used in several vaccine candidates. QS-21 strongly potentiates both cellular and humoral immune responses to purified antigens, yet how it activates immune cells is largely unknown. Here, we report that QS-21 directly activated human monocyte-derived dendritic cells (m...
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ژورنال
عنوان ژورنال: Arthritis & Rheumatism
سال: 1972
ISSN: 0004-3591,1529-0131
DOI: 10.1002/art.1780150203